39 Results for "

Programmed cell death ligand 1 (PD-L1)

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "Programmed cell death ligand 1 (PD-L1)" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-P73361
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1
Species:  
Source:  
4
4 Cited Publications
Cat. No.: HY-N0596
CAS No.: 19666-76-3
Synonyms: 20(R)-Panaxadiol
Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities .
3
3 Cited Publications
Cat. No.: HY-P99052
CAS No.: 1858168-59-8
Synonyms: BGB-A317

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma .
2
2 Cited Publications
Cat. No.: HY-P70632
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1Cd274; Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274
Species:  
Source:  
1
1 Cited Publications
Cat. No.: HY-P84982
Synonyms: Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD antigen CD274; CD274 nanobody; PD-L1 nanobody;

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

Cat. No.: HY-P10439
CAS No.: 2349354-64-7
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

CVRARTR is a programmed cell death ligand-1 (PD-L1) antagonist with a KD of 281 nM. CVRARTR induces the internalization of PD-L1 and downregulates PD-L1 on the cell surface. CVRARTR restores cytokine secretion and T cell proliferation in cell CT26. CVRARTR exhibits antitumor efficacy against in CT26 homograft mouse model. CVRARTR can be used in melanoma research .
Cat. No.: HY-P99618
CAS No.: 2377419-89-9
Synonyms: IBI-315; BH2950

Target:  

EGFR PD-1/PD-L1

Research Areas:  

Cancer

Fidasimtamab is a bispecific antibody targeting human epidermal growth factor receptor 2 (Her2) and programmed death protein 1 (PD-1), with a Ka of 3.55e-10 M for human Her2 and a Ka of 1.17e-9 M for human PD-1. Fidasimtamab cross-links Her2-positive tumor cells with PD-1-positive T cells to form immune synapses, blocks PD-1-ligand interactions, preserves antibody-dependent cellular cytotoxicity, induces gasdermin B (GSDMB)-mediated pyroptosis, and activates T cells. Fidasimtamab is applicable to relevant research on Her2-positive gastric cancer .
Cat. No.: HY-P99114
CAS No.: 2256084-03-2

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .
Cat. No.: HY-P10950A
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

PD-L1 inhibitory peptide TFA is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1). PD-L1 inhibitory peptide TFA binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells. PD-L1 inhibitory peptide TFA is promising for research of cancers .
Cat. No.: HY-128605
CAS No.: 2349372-98-9
Purity:  98.99%
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM .
Cat. No.: HY-P10950
CAS No.: 1931111-41-9
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

PD-L1 inhibitory peptide is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1). PD-L1 inhibitory peptide binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells. PD-L1 inhibitory peptide is promising for research of cancers .
Cat. No.: HY-151066
CAS No.: 2447065-99-6
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMS-1233 is an orally active inhibitor for programmed cell death-ligand 1 (PD-L1), with IC50 of 14.5 nM. BMS-1233 promotes cell death of HepG2 in a Jurkat T cell and HepG2 cell co-culture model, exhibits antitumor activity against melanoma in mouse model .
Cat. No.: HY-P990757
CAS No.: 2763222-58-6
Synonyms: ABL503, TJ-L14B

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Ragistomig can simultaneously target programmed death-ligand 1 (PD-L1) and the 4-1BB receptor. Ragistomig elicits potent anti-tumor T-cell responses without inducing significant toxicity. Ragistomig is applicable for tumor research .
Cat. No.: HY-158052
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1/PD-L1 antagonist 1 (Compound A5) is an antagonist for programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1) interaction, with an IC50 of 23.78 nM .
Cat. No.: HY-P70633
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1Cd274; Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274;
Species:  
Source:  
Cat. No.: HY-P73364
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1
Species:  
Rat
Source:  
Cat. No.: HY-P73365
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1
Species:  
Rat
Source:  
Cat. No.: HY-P73717
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1
Species:  
Source:  
Cat. No.: HY-P73716
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1
Species:  
Source:  
Cat. No.: HY-P70657
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 Homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Species:  
Source: